Chagas' heart disease: clinical-pathological correlation.
نویسندگان
چکیده
This review provides an overview of the clinicopathological aspects of chronic Chagas' heart disease, and a comprehensive view of predictors of mortality for chagasic patients with Chagas' cardiopathy in an attempt to help physicians with the management of their patients.
منابع مشابه
Frequency of hypertension in patients with chronic Chagas disease and its consequences on the heart: a clinical and pathological study.
BACKGROUND Data from the literature on the frequency of concomitant Chagas disease and hypertension are controversial and, when available, do not mention the consequences of this concomitance in the natural history of either Chagas disease or of hypertension. OBJECTIVE To assess the frequency of concomitant Chagas disease and hypertension and the clinical and anatomopathological consequences ...
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Chagas disease is caused by Trypanosoma cruzi and remains a health problem in the developing countries of South America. The condition leads to cardiac conduction disturbances and chronic heart failure. In this study, 136 individuals were evaluated by the Chagas Disease Study Group of the Hospital de la Universidad Estatal de Campinas in Brazil to determine the relationship between chronic hear...
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Several independent pathological studies in experimental models and in human beings showed conspicuous autonomic denervation in Chagas' disease. In spite of the inherently complex structural organization of the autonomic nervous system, the parasympathetic and sympathetic divisions are involved, as shown by many functional studies. Hence, Chagas' disease represents a unique model of impairment ...
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Chagas cardiomyopathy is the most severe clinical manifestation of chronic Chagas disease. The disease affects most of the Latin American countries, being considered one of the leading causes of morbidity and death in the continent. The pathogenesis of Chagas cardiomyopathy is very complex, with mechanisms involving parasite-dependent cytopathy, immune-mediated myocardial damage and neurogenic ...
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Thirteen patients (mean aged 48 ± 3 years, nine male) with chronic Chagas’ heart disease, defined as positive serology and epidemiological history, were investigated in a clinical trial designed to analyze the correlation between cardiac sympathetic denervation and myocardial perfusion changes8. They had normal global systolic ventricular function (LV ejection fraction was 55 ± 2%) and no ventr...
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ورودعنوان ژورنال:
- Frontiers in bioscience : a journal and virtual library
دوره 8 شماره
صفحات -
تاریخ انتشار 2003